Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published July 1965 | public
Journal Article

The Process of Infection with Bacteriophage φX174: III. Phage Maturation and Lysis after Synchronized Infection

Abstract

Techniques are described for the synchronization of the infection by bacteriophage φX174 in all of the infected bacteria. One-step growth curves of wild-type φX and of a mutant with a longer mean latent period have been determined. The rate of appearance of mature phage is constant, and phage release is accompanied by cellular dissolution.

Additional Information

© 1965 Elsevier Ltd. Received 29 December 1964, and in revised form 22 March 1965. This work was reported in a thesis submitted to the California Institute of Technology by one of us (D.T.D.) in partial fulfilment of the requirements for the degree of Doctor of Philosophy. Financial support was provided by fellowships from the National Science Foundation and the Public Health Service and by grant RG 6965 of the U.S. Public Health Service. We wish to acknowledge many informative discussions with Dr R. S. Edgar and Mr Clyde Hutchison.

Additional details

Created:
August 19, 2023
Modified:
October 19, 2023