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Published April 1964 | public
Journal Article

The u.v.-Resistance of Double-stranded φX174 DNA

Abstract

The infective, intracellular form of bacteriophage φX174 DNA has been reported to be much more resistant to inactivation by u.v. irradiation than is" the infective single-stranded DNA isolated from mature virus. The tenfold smaller inactivation cross-section of the RFt is consistent with its postulated double-stranded structure (Sinsheimer, Starman, Nagler & Guthrie, 1962).

Additional Information

© 1964 Elsevier Ltd. Received 14 February 1964. After this work was submitted a note by Jansz, Pouwels & van Rotterdam (1963) appeared in which similar experiments were reported. This research was supported in part by grant RG 6965 from the National Institutes of Health and in part by fellowship 1F1 GM21, 328-01 of the USPHS.

Additional details

Created:
August 19, 2023
Modified:
October 19, 2023