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Published June 14, 1967 | public
Journal Article

The Replication of Bacteriophage MS2: VII. Non-conservative Replication of Double-stranded RNA

Abstract

The replication of phage-specific RNA duplexes in cells infected with the bacteriophage MS2 has been studied by means of density labeling and CsCl equilibrium density sedimentation. It was found that the input parental RNA strand enters a duplex and that progeny duplexes appear soon afterwards, with approximately exponential kinetics. Chase experiments indicate that most of the parental and progeny duplexes are not conserved.

Additional Information

© 1967 Elsevier Ltd. Received 25 January 1967. This work was supported by grants RG6965 and GM13554 from the U.S. Public Health Service.

Additional details

Created:
August 19, 2023
Modified:
October 18, 2023