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Published July 5, 2004 | Supplemental Material
Journal Article Open

Design of a sequence-specific DNA bisintercalator

Abstract

Programmable bisintercalators: Symmetric synthetic DNA bisintercalators (see picture) based on the H-pin polyamide motif afford high affinity and programmable sequence specificity.

Additional Information

©� 2004 Wiley-VCH. Received: March 10, 2004. We thank the National Institutes of Health (GM-27681) for research support, a Research Service Award to E.J.F., and a postdoctoral fellowship to B.O. (F32 GM-19788). We also thank the Ralph M. Parsons Foundation for a predoctoral fellowship to E.J.F.

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