Published April 2016
| public
Journal Article
Moduli spaces and macromolecules
- Creators
- Penner, R. C.
Abstract
Techniques from moduli spaces are applied to biological macromolecules. The first main result provides new a priori constraints on protein geometry discovered empirically and confirmed computationally. The second main result identifies up to homotopy the natural moduli space of several interacting RNA molecules with the Riemann moduli space of a surface with several boundary components in each fixed genus. Applications to RNA folding prediction are discussed. The mathematical and biological frameworks are surveyed and presented from first principles.
Additional Information
© 2016 American Mathematical Society. Received by the editors August 24, 2015. Published electronically: February 3, 2016. Bill Goldman, Piotr Sułkowski and especially Fenix Huang, Nadya Morozova, and Scott Wolpert provided helpful comments and critical readings. Further thanks are due to Ebbe Andersen for assistance with the figures and for many useful comments.Additional details
- Eprint ID
- 66726
- DOI
- 10.1090/bull/1524
- Resolver ID
- CaltechAUTHORS:20160509-083001905
- Created
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2016-05-09Created from EPrint's datestamp field
- Updated
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2021-11-11Created from EPrint's last_modified field