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Published June 20, 1997 | public
Journal Article

Leukemia inhibitory factor (LIF) mRNA-expressing neuronal subpopulations in adult rat basal forebrain

Abstract

We have previously found leukemia inhibitory factor (LIF) mRNA in neurons of the adult rat brain. To identify which neuronal subpopulations are expressing LIF transcripts, non-radioactive in situ hybridization was combined with immunocytochemistry for various neuronal markers. Studying the rat basal forebrain and cerebral cortex, we find LIF mRNA is expressed in both cholinergic and GABAergic neurons. These data suggest a role for LIF in the function of these mature neurons.

Additional Information

© 1997 Elsevier Science Ireland Ltd. Received 2 April 1997; received in revised form 2 June 1997; accepted 2 June 1997. Available online 23 July 1997. This work was supported by the University of Leipzig Medical Faculty, grant no. 762116 to R.S. and by a grant from the NIH to P.H.P. R.L. is a recipient of a stipend from the Studienstiftung des Deutschen Volkes e.V., and R.A.G. is supported by the Swiss National Science Foundation and the Roche Research Foundation.

Additional details

Created:
August 22, 2023
Modified:
October 18, 2023