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Published April 21, 2016 | Submitted
Journal Article Open

Statistical mechanics of neocortical interactions: Large-scale EEG influences on molecular processes

Ingber, Lester

Abstract

Calculations further support the premise that large-scale synchronous firings of neurons may affect molecular processes. The context is scalp electroencephalography (EEG) during short-term memory (STM) tasks. The mechanism considered is Π=p+qA (SI units) coupling, where p is the momenta of free Ca2+ waves, q the charge of Ca^(2+) in units of the electron charge, and A the magnetic vector potential of current I from neuronal minicolumnar firings considered as wires, giving rise to EEG. Data has processed using multiple graphs to identify sections of data to which spline-Laplacian transformations are applied, to fit the statistical mechanics of neocortical interactions (SMNI) model to EEG data, sensitive to synaptic interactions subject to modification by Ca^(2+) waves.

Additional Information

© 2016 Elsevier B.V. Received 23 December 2015, Revised 23 January 2016, Accepted 1 February 2016, Available online 11 February 2016. I thank the National Science Foundation's Extreme Science and Engineering Discovery Environment (XSEDE.org), for three supercomputer grants since February 2013, "Electroencephalographic field influence on calcium momentum waves", one under PHY130022 and two under TG-MCB140110. I thank Ramesh Srinivasan for giving me part of his Matlab code for spline-Laplacian scalp transformations.

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