International Symposium on the Nucleolus, Its Structure and Function [Book Review]

Abstract

This to the best of my knowledge is the first book to be devoted in its entirety to the nucleolus. It's a thick book that contains the thoughts of some 75 speakers, co-authors, and discussants and considers the nucleolus from most of the possible viewpoints. From this massive amount of information two clear-cut take-home lessons emerge: first, that although nucleoli of different creatures look different by light microscopy, they are all remarkably similar in fine structure, composed as they are of coarse fibers, fine fibers, and granules; and second, that the nucleolus is made by the nucleolar organizer, which we already knew, and that the nucleolar organizer contains the genetic material responsible for the coding of ribosomal RNA.

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