Syntheses of Some 4-Substituted Bicyclo [2.2.2]octane-1-carboxylic Acids

Creators: Roberts, John D.; Moreland, Walter T.; Frazer, Winifred

Abstract

A series of 4-substituted bicyclo [2.2.2]octane-1-carboxylic acids and ethyl esters with X = H, Br, -OH, -CO_2C_2H_6, -NH_2 and -C=N has been synthesized from diethyl 2,5-dioxobicyclo[ 2.2.2]octane-1,4-dicarboxylate.

Additional Information

© 1953 American Chemical Society. Received August 11, 1952. Presented before the Division of Organic Chemistry at the Atlantic City Meeting of the American Chemical Society, September, 1952. U. S. Atomic Energy Commission Predoctoral Fellow 1951-1952.

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Resource type: Journal Article
Publisher: American Chemical Society
Published in: Journal of the American Chemical Society, 75(3), 637-640, ISSN: 0002-7863.
Conference: Meeting of the American Chemical Society, Atlantic City, NJ, September 1952

Created:: August 19, 2023
Modified:: October 25, 2023