Nuclear Magnetic Resonance Spectroscopy. Carbon-13 Spectra of Steroids
Abstract
The natural abundance ^(13)C resonance spectra of a variety of sterols and steroidal hormones have been determined at 15.1 MHz. The chemical shifts of the carbons in these substances were found to span on the order of 200 ppm and for most steroids with the aid of complete proton decoupling it was possible to resolve all of the carbon resonances one from the other. It has also been possible by using specific single-frequency and off-resonance proton decoupling, hydroxyl acetylation effects on chemical shifts, deuteration, and substituent influences in analogous compounds to make self-consistent and unambiguous assignments of nearly all of the resonances encountered. The carbon resonances are in general far more informative than proton resonances for structural analysis of steroids.
Additional Information
© 1969 American Chemical Society. Received June 30, 1969. Supported in part by the Public Health Service, Research Grant 11072-06 from the Division of General Medical Sciences, and the National Science Foundation. National Research Council of Canada Postdoctoral Fellow, 1968-1969. Participant in the Undergraduate Research Program of the National Science Foundation, National Science Foundation Predoctoral Fellow, 1965- 1968.Additional details
- Eprint ID
- 61067
- DOI
- 10.1021/ja01054a037
- Resolver ID
- CaltechAUTHORS:20151013-145410498
- GM-11072-05-06
- U.S. Public Health Service (USPHS)
- NSF
- National Research Council of Canada
- NSF Undergraduate Research Program
- National Science Foundation predoctoral fellowship
- Created
-
2015-10-14Created from EPrint's datestamp field
- Updated
-
2021-11-10Created from EPrint's last_modified field
- Other Numbering System Name
- Caltech Gates and Crellin Laboratories of Chemistry
- Other Numbering System Identifier
- 3889