Published September 1, 1977
| public
Journal Article
The protonation site of vitamin B_1 as determined from natural-abundance nitrogen-15 nuclear magnetic resonance spectra
Abstract
Natural-abundance nitrogen-15 nuclear magnetic resonance spectroscopy has been used to determine the site of protonation in vitamin B_1. Selectively decoupling individual protons of the vitamin in water, D_2O, and ethylene glycol permitted assignment of the nitrogen resonances and thence the determination of the site of protonation, which was found to be N-1 of the pyrimidine ring.
Additional Information
© 1977 American Chemical Society. Received January 19, 1977. Supported in part by the National Science Foundation and by the Public Health Service, Research Grant 11072 from the division of General Medical Science.Additional details
- Eprint ID
- 60891
- Resolver ID
- CaltechAUTHORS:20151008-070944702
- NSF
- GM-11072
- U.S. Public Health Service (USPHS)
- Created
-
2015-10-08Created from EPrint's datestamp field
- Updated
-
2021-11-10Created from EPrint's last_modified field
- Other Numbering System Name
- Caltech Gates and Crellin Laboratories of Chemistry
- Other Numbering System Identifier
- 5496