Published May 1, 1979
| public
Journal Article
Nitrogen-15 nuclear magnetic resonance spectroscopy. Effects of hydrogen bonding and protonation on nitrogen chemical shifts of pyrazoles
Abstract
The ^(15)N chemical shifts of pyrazole, N-methylpyrazole, 3-methyl- and 3,5-dimethylpyrazoles, and indazole have been measured as a function of solvent and acidity of the medium. Hydrogen bonding and protonation result in upfield shifts of both the pyridine- and pyrrole-type nitrogen resonances of these substances with the effect being larger a t the pyridine-type nitrogens. The protonation shifts far exceed those resulting from hydrogen bonding.
Additional Information
© 1979 American Chemical Society. Received September 5, 1978. Supported by the National Science Foundation and by the Public Health Service. Research Grant No. GM-11072 from the Division of General Medical Sciences.Additional details
- Eprint ID
- 60859
- DOI
- 10.1021/jo01325a003
- Resolver ID
- CaltechAUTHORS:20151007-093102214
- NSF
- GM-11072
- U.S. Public Health Service (USPHS)
- Created
-
2015-10-07Created from EPrint's datestamp field
- Updated
-
2021-11-10Created from EPrint's last_modified field
- Other Numbering System Name
- Caltech Gates and Crellin Laboratories of Chemistry
- Other Numbering System Identifier
- 5874