Published February 1982
| public
Journal Article
Nitrogen-15 Nuclear Magnetic Resonance Spectroscopy. N—H Proton Exchange Reactions of Urea, Thiourea, Acetamide and Thioacetamide
- Creators
- Chun, Yu
- Yavari, Issa
- Roberts, John D.
Abstract
Measurements are reported of NH exchange rates of urea, thiourea, acetamide and thioacetamide, using line-shape analysis with natural-abundance ^(15)N NMR spectra. Base-catalyzed NH-proton exchange of thiourea is 30–40 times faster than for urea, while the corresponding acid-catalyzed exchange is 150 times slower. The base-catalyzed proton exchange for thioacetamide is about 1000 times faster than that of acetamide at 25°C, while the corresponding acid-catalyzed exchange is some 260 times slower.
Additional Information
© 1982 Heyden & Son Ltd. Received 22 January 1981 ; accepted 31 August 1981. Supported by the Public Health Service, Research Grant No. GM-11072 from the Division of General Medical Sciences, and by the National Science Foundation.Additional details
- Eprint ID
- 60765
- DOI
- 10.1002/mrc.1270180205
- Resolver ID
- CaltechAUTHORS:20151005-120248654
- GM-11072
- U.S. Public Health Service (USPHS)
- NSF
- Created
-
2015-10-05Created from EPrint's datestamp field
- Updated
-
2021-11-10Created from EPrint's last_modified field
- Other Numbering System Name
- Caltech Gates and CreUjn Laboratories of Chemistr
- Other Numbering System Identifier
- 6378