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Published February 1983 | public
Journal Article

^(15)N NMR studies of biological systems

Abstract

Nitrogen is widely distributed in biological systems and is often directly involved in biochemical processes of interest. Nitrogen-15 nuclear magnetic resonance (^(15)N NMR) spectroscopy is, therefore, potentially a very valuable technique for the study of biological systems. Within the last several years, a number of exciting, pioneering ^(15)N NMR studies of biomolecules have been reported, and this review will describe several of these in three areas of biochemistry: (1) proteins including proteolytic enzymes and hemoproteins, (2) nucleic acids and nucleotide bases and their interactions in base pairing and drug binding, and (3) in vivo metabolism and cellular dynamics in intact microorganisms and plants.

Additional Information

© 1983 American Chemical Society. Received April 15, 1982 Revised Manuscript Received September 13, 1982. Publication Date: February 1983. We are pleased to acknowledge support by the National Science Foundation and by the Public Health Service, Grant No. GM-11072 from the Division of General Medical Sciences.

Additional details

Created:
August 19, 2023
Modified:
October 24, 2023