Neurons in the human amygdala encode face identity, but not gaze direction
Abstract
The amygdala is important for face processing, and direction of eye gaze is one of the most socially salient facial signals. Recording from over 200 neurons in the amygdala of neurosurgical patients, we found robust encoding of the identity of neutral-expression faces, but not of their direction of gaze. Processing of gaze direction may rely on a predominantly cortical network rather than the amygdala.
Additional Information
© 2015 Macmillan Publishers Limited. Received 29 July 2015. Accepted 17 September 2015. Published online 19 October 2015. We thank all patients for their participation and B. Samimizad for assistance with the spike sorting. This research was supported by the Volkswagen Foundation and the German Research Council (DFG, MO 930/4-1 and SFB 1089), a Conte Center grant from NIMH (P50 MH094258), and a grant from the Simons Foundation (SFARI Director's award). Contributions: F.M. and R.A. designed the study. F.M. and O.T. implemented the experimental procedure. V.A.C. and F.M. carried out the neurosurgical procedures. F.M. and J.N. collected the electrophysiological data. F.M. analyzed the electrophysiological data. C.M.Q., J.N., C.E.E. and F.M. verified electrode locations. R.A. and F.M. wrote the paper. All of the authors discussed the results and commented on the manuscript. The authors declare no competing financial interests.Attached Files
Accepted Version - nihms724263.pdf
Supplemental Material - nn.4139-S1.pdf
Supplemental Material - nn.4139-S2.pdf
Supplemental Material - nn.4139-SF1.jpg
Supplemental Material - nn.4139-SF2.jpg
Supplemental Material - nn.4139-SF3.jpg
Supplemental Material - nn.4139-SF4.jpg
Supplemental Material - nn.4139-SF5.jpg
Supplemental Material - nn.4139-SF6.jpg
Supplemental Material - nn.4139-SF7.jpg
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Additional details
- PMCID
- PMC4624486
- Eprint ID
- 60275
- Resolver ID
- CaltechAUTHORS:20150916-102243687
- Volkswagen Foundation
- MO 930/4-1
- Deutsche Forschungsgemeinschaft (DFG)
- SFB 1089
- Deutsche Forschungsgemeinschaft (DFG)
- P50 MH094258
- NIH
- Simons Foundation
- National Institute of Mental Health (NIMH)
- Created
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2015-10-27Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field