Published October 8, 1976
| public
Journal Article
Depletion of brain catecholamines: failure of ocular dominance shift after monocular occlusion in kittens
- Creators
- Kasamatsu, Takuji
- Pettigrew, John D.
Abstract
Monocularly deprived kittens were compared with littermates that had had their eyelids sutured for the same time but that had, in addition, been treated with 6-hydroxydopamine to deplete their forebrains of catecholamines. The visual cortices of all the catecholamine-depleted kittens showed high proportions of binocular neurons, in contrast to the control group, most of whose visual cortical neurons were driven exclusively by the nondeprived eye. Catecholamines may play an important role in the maintenance of cortical plasticity during the critical period.
Additional Information
© 1976 American Association for the Advancement of Science. Received 1 March 1976; Revised 7 June 1976. Supported by NIMH grant MH25852 and by the Spencer Foundation. We thank Lederle Laboratories for providing us with Flaxedil.Additional details
- Eprint ID
- 58716
- Resolver ID
- CaltechAUTHORS:20150630-160750039
- MH25852
- National Institute of Mental Health (NIMH)
- Spencer Foundation
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2015-07-01Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field