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Published August 2004 | Supplemental Material
Journal Article Open

Multiplexing using synchrony in the zebrafish olfactory bulb

Abstract

In the olfactory bulb (OB) of zebrafish and other species, odors evoke fast oscillatory population activity and specific firing rate patterns across mitral cells (MCs). This activity evolves over a few hundred milliseconds from the onset of the odor stimulus. Action potentials of odor-specific MC subsets phase-lock to the oscillation, defining small and distributed ensembles within the MC population output. We found that oscillatory field potentials in the zebrafish OB propagate across the OB in waves. Phase-locked MC action potentials, however, were synchronized without a time lag. Firing rate patterns across MCs analyzed with low temporal resolution were informative about odor identity. When the sensitivity for phase-locked spiking was increased, activity patterns became progressively more informative about odor category. Hence, information about complementary stimulus features is conveyed simultaneously by the same population of neurons and can be retrieved selectively by biologically plausible mechanisms, indicating that seemingly alternative coding strategies operating on different time scales may coexist.

Additional Information

© 2004 Nature Publishing Group. Received 22 March 2004; Accepted 11 June 2004; Published online: 25 July 2004. We thank A. Schäfer and members of the Friedrich and Laurent labs for helpful discussions and/or comments on the manuscript. This work was supported by the Max-Planck Society, the Deutsche Forschungsgemeinschaft (DFG), the National Institutes for Deafness and other Communication Disorders (NIDCD), the Keck Foundation and the McKnight Foundation.

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Supplemental Material - nn1292-S8.pdf

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Additional details

Created:
August 19, 2023
Modified:
October 23, 2023