Published September 7, 2000
| public
Journal Article
Investigating T-cell memory
- Creators
- Mantovani, Alberto
Abstract
Memory is a long-recognized, crucial and poorly understood property of adaptive immunity. Jacob and Baltimore have designed an elegant genetic approach to marking memory T cells and their precursors irreversibly and have obtained intriguing results. I suggest that the particular enzyme (human placental alkaline phosphatase) chosen for irreversible marking in postnatal life contributes to certain features of this system and perturbs the homeostatic mechanisms of T-cell activation and death.
Additional Information
© 2000 Macmillan Magazines Ltd.Additional details
- Eprint ID
- 56214
- DOI
- 10.1038/35024159
- Resolver ID
- CaltechAUTHORS:20150330-110250643
- Created
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2015-03-30Created from EPrint's datestamp field
- Updated
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2021-11-10Created from EPrint's last_modified field