Olefin Cross-Metathesis

Abstract

Olefin cross-metathesis has become an indispensable tool for efficient carbon–carbon bond formation. Fundamental studies on functional group tolerance and an understanding of the steric and electronic factors crucial to product selectivity have led to the development of an empirical model for reaction design. Due to the copious amount of recent literature pertaining to this reaction, this review focuses on reports pertaining to important aspects in either the concept or the application of alkene cross-metathesis. Strategies for effecting highly selective cross-metathesis reactions will be presented and discussed.

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