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Published May 22, 2014 | public
Journal Article

Engineering Recombinant AAV Vectors for More Efficient and Restricted Gene Expression in the CNS after Systemic Administration

Abstract

We previously demonstrated that delivery of the cytokine leukemia inhibitory factor (LIF) to the brain by recombinant adenovirus enhances oligodendrocyte progenitor cell proliferation and remyelination in a mouse model of multiple sclerosis (MS).

Additional Information

© 2014 American Society of Gene & Cell Therapy.

Additional details

Created:
August 20, 2023
Modified:
October 26, 2023