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Published 2013 | Accepted Version
Book Section - Chapter Open

Leaderless Deterministic Chemical Reaction Networks

Abstract

This paper answers an open question of Chen, Doty, and Soloveichik [5], who showed that a function f:ℕ^(k)  → ℕ^(l) is deterministically computable by a stochastic chemical reaction network (CRN) if and only if the graph of f is a semilinear subset of ℕ^(k + l) . That construction crucially used "leaders": the ability to start in an initial configuration with constant but non-zero counts of species other than the k species X_(1,…,X_k) representing the input to the function f. The authors asked whether deterministic CRNs without a leader retain the same power. We answer this question affirmatively, showing that every semilinear function is deterministically computable by a CRN whose initial configuration contains only the input species X_(1,…,X_k), and zero counts of every other species. We show that this CRN completes in expected time O(n), where n is the total number of input molecules. This time bound is slower than the O(log^5 n) achieved in [5], but faster than the O(n logn) achieved by the direct construction of [5].

Additional Information

© 2013 Springer International Publishing Switzerland. We are indebted to Anne Condon for helpful discussions and suggestions. This author was supported by the Molecular Programming Project under NSF grant 0832824 and by NSF grants CCF-1219274 and CCF-1162589.

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August 19, 2023
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