Myotypic Respecification of Regenerated Nerve-fibres in Cichlid Fishes
- Creators
- Arora, H. L.
- Sperry, R. W.
Abstract
In man and other mammals normal motor co-ordination is not restored, as a rule, after regeneration of a severed peripheral nerve-trunk (Sperry, 1945). The random misdirection of regenerating fibres into foreign muscles tends to prevent normal dissociated action within the re-innervated musculature. In contrast, larval amphibians have been found to show excellent recovery of motor function in the form of 'homologous or myotypic response' (Weiss, 1936, 1941) following the cutting and regeneration of limb-nerves, limb transplantation, and the cross-connecting of limb nerves to foreign muscles. Similarly, good restoration of muscle co-ordination has been observed in the pectoral fin of adult teleost fishes (Sperry, 1950, 1956).
Additional Information
© 1957 Company of Biologists. Received September 18, 1956. This investigation was supported by the F. P. Hixon Fund of the California Institute of Technology and a grant from Eli Lilly and Company.Attached Files
Published - AROjeem57.pdf
Files
Name | Size | Download all |
---|---|---|
md5:c530387e872b1c7b27954324ab4928cb
|
460.1 kB | Preview Download |
Additional details
- Eprint ID
- 45749
- Resolver ID
- CaltechAUTHORS:20140514-143251140
- Caltech F. P. Hixon Fund
- Eli Lilly and Company grant
- Created
-
2014-05-14Created from EPrint's datestamp field
- Updated
-
2019-10-03Created from EPrint's last_modified field