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Published September 2013 | Accepted Version
Journal Article Open

Design standards for engineered tissues

Abstract

Traditional technologies are required to meet specific, quantitative standards of safety and performance. In tissue engineering, similar standards will have to be developed to enable routine clinical use and customized tissue fabrication. In this essay, we discuss a framework of concepts leading towards general design standards for tissue-engineering, focusing in particular on systematic design strategies, control of cell behavior, physiological scaling, fabrication modes and functional evaluation.

Additional Information

© 2013 Elsevier Inc. Available online 23 December 2012. We acknowledge financial support from US National Institutes of Health grant 1 R01 HL079126 (K.K.P.).

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