Published 2000
| public
Journal Article
The role of single neurons in information processing
- Creators
-
Koch, Christof
- Segev, Idan
Abstract
Neurons carry out the many operations that extract meaningful information from sensory receptor arrays at the organism's periphery and translate these into action, imagery and memory. Within today's dominant computational paradigm, these operations, involving synapses, membrane ionic channels and changes in membrane potential, are thought of as steps in an algorithm or as computations. The role of neurons in these computations has evolved conceptually from that of a simple integrator of synaptic inputs until a threshold is reached and an output pulse is initiated, to a much more sophisticated processor with mixed analog-digital logic and highly adaptive synaptic elements.
Additional Information
© 2000 Nature America Inc. Received 7 June; Accepted 29 September 2000. Work in the laboratories of the authors is supported by the NSF/ERC program, NIMH, ONR, Israeli Science Foundation and the BSF. We thank R. Nitzan for Fig. 2a, Y. Manor for Fig. 2b, J. Andersen for the two pyramidal cells in Fig. 2c and d, M. Rapp for Fig. 2e, B. Burke for Fig. 2f, M. Larkum for Fig. 3, F. Gabbiani for Fig. 4 and F. Gabbiani and G. Kreiman for comments.Additional details
- Eprint ID
- 40575
- DOI
- 10.1038/81444
- Resolver ID
- CaltechAUTHORS:20130816-103250693
- NSF/ERC program
- National Institute of Mental Health (NIMH)
- Office of Naval Research (ONR)
- Israeli Science Foundation
- Binational Science Foundation (USA-Israel)
- Created
-
2008-01-16Created from EPrint's datestamp field
- Updated
-
2021-11-09Created from EPrint's last_modified field
- Caltech groups
- Koch Laboratory (KLAB)