Published June 2013
| public
Journal Article
Design and Synthesis of Oligoamide-Based Double α-Helix Mimetics
Abstract
An extensive series of bis-oligobenzamides and bis-oligopyridylamides have been efficiently prepared and studied by X-ray analysis and computational methods. A modular synthesis led to double -helix mimics bearing between two and ten branched side-chains. The inter-helix angle and distance can be tuned by varying the length and rigidity of the spacer, thereby reproducing the recognition domains of a range of super-secondary structures.
Additional Information
© 2013 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Received: March 10, 2013; published Online: May 23, 2013. The authors thank the National Science Foundation (NSF) (CHE-0750357), National Institutes of Health (NIH) (CA67771) and the University of Oxford, UK for funding.Additional details
- Eprint ID
- 39336
- DOI
- 10.1002/ejoc.201300363
- Resolver ID
- CaltechAUTHORS:20130712-102051387
- CHE-0750357
- NSF
- CA67771
- NIH
- University of Oxford
- Created
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2013-07-15Created from EPrint's datestamp field
- Updated
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2021-11-09Created from EPrint's last_modified field