Published January 2012
| public
Book Section - Chapter
A 3D parylene scaffold cage for culturing retinal pigment epithelial cells
Abstract
This work reports a 3D parylene scaffold cage for culturing stem-cell-differentiated retinal pigment epithelial (RPE) cells for the therapy of age-related macular degeneration, which is caused by degenerated permeability of the Bruch's membrane first and then the loss of RPE cells. This reported cage can support sufficient nutrient permeation to nourish the RPE cells inside with in vivo like morphology. Compared to previous single layer scaffold substrates, this cage can effectively prevent the undesirable cell migration away from the scaffold.
Additional Information
© 2012 IEEE. Date of Current Version: 15 March 2012. This work is supported by the California Institute of Regenerative Medicine (CIRM); Disease Team Award; Grant DR1-01444.Additional details
- Eprint ID
- 36731
- DOI
- 10.1109/MEMSYS.2012.6170292
- Resolver ID
- CaltechAUTHORS:20130201-100453140
- DR1-01444
- California Institute of Regenerative Medicine (CIRM)
- Created
-
2013-02-25Created from EPrint's datestamp field
- Updated
-
2021-11-09Created from EPrint's last_modified field
- Other Numbering System Name
- INSPEC Accession Number
- Other Numbering System Identifier
- 12618136