Published April 1973
| Published
Journal Article
Open
Identification of the Vesicular Stomatitis Virus Large Protein as a Unique Viral Protein
- Creators
- Stampfer, Martha
-
Baltimore, David
Abstract
Previous studies have noted the existence of a 190,000-daltoin vesicular stomatitis virus (VSV) protein called the large (L) protein. To determine whether this protein is a nonspecific aggregate, a precursor to the other VSV proteins, or a unique viral protein, its synthesis relative to the other VSV proteins was studied under conditions of inhibition of initiation of protein synthesis. Also, its tryptic peptides were compared to those of the other VSV proteins. In both cases the results were consistent with the identification of the large protein as a unique viral protein.
Additional Information
© 1973 American Society for Microbiology. Received for publication 30 November 1972. We thank Nora Meuth for technical assistance. This work was supported by a grant from the American Cancer Society. M. S. was a predoctoral fellow of the National Science Foundation, and D. B. was a Faculty Research Awardee of the American Cancer Society.Attached Files
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Additional details
- PMCID
- PMC355133
- Eprint ID
- 32996
- Resolver ID
- CaltechAUTHORS:20120807-161758173
- American Cancer Society
- NSF
- Created
-
2012-08-07Created from EPrint's datestamp field
- Updated
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2019-10-03Created from EPrint's last_modified field