Published October 1985
| Published
Journal Article
Open
Monoclonal antibodies to the cells of a regenerating limb
- Creators
- Kintner, Chris R.
- Brockes, Jeremy P.
Abstract
Monoclonal antibodies were raised against differentiated cells, and blastemal cells from regenerating limbs of adult newts (Notophthalmus viridescens) and screened for specific staining by immunocytochemistry. In addition to antibodies that identify muscle, Schwann cells and cartilage, two reagents were specific for subpopulations of blastemal cells. One of these latter antibodies, termed 22/18, has provided new evidence about the origin of blastemal cells from Schwann cells and rnyofibres, and also identifies blastemal cells whose division is persistently dependent on the nerve supply.
Additional Information
© 1985 The Company of Biologists Limited. Accepted 26 April 1985. We would like to thank Sarah Joslin for excellent technical assistance and Drs Donna Fekete, Herman Gordon, Nigel Holder and Russel Fernald for critical reading of the manuscript. C.K. was supported by a NRSA fellowship from the National Institute of Health.Attached Files
Published - KINjeem85.pdf
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Additional details
- Eprint ID
- 32190
- Resolver ID
- CaltechAUTHORS:20120629-090859602
- NIH NRSA Fellowship
- Created
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2012-07-02Created from EPrint's datestamp field
- Updated
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2019-10-03Created from EPrint's last_modified field