Published July 26, 2010
| Supplemental Material + Accepted Version
Journal Article
Open
Gold-Catalyzed Intramolecular Aminoarylation of Alkenes: C-C Bond Formation through Bimolecular Reductive Elimination
Abstract
Gold-ilocks and the 3 mol % catalyst: Bimetallic gold bromides allow the room temperature aminoarylation of unactivated terminal olefins with aryl boronic acids using Selectfluor as an oxidant. A catalytic cycle involving gold(I)/gold(III) and a bimolecular reductive elimination for the key CC bond-forming step is proposed. dppm= bis(diphenylphosphanyl)methane.
Additional Information
© 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Received: May 6, 2010. Published online: July 2, 2010. F.D.T. gratefully acknowledges NIHGMS (R01 GM073932-04S1), Novartis, and Amgen for funding and Johnson Matthey for a generous donation of AuCl3. The MSC computational facilities were funded by grants from ARO-DURIP and ONR-DURIP.Attached Files
Accepted Version - nihms-226820.pdf
Supplemental Material - anie_201002739_sm_miscellaneous_information.pdf
Files
anie_201002739_sm_miscellaneous_information.pdf
Files
(1.7 MB)
| Name | Size | Download all |
|---|---|---|
|
md5:0b139b4c8d1dfea93c583c09c0be3c4b
|
1.3 MB | Preview Download |
|
md5:52e89ff4f95e454b0db97ce1f11ef99f
|
378.8 kB | Preview Download |
Additional details
- PMCID
- PMC3433283
- Eprint ID
- 19719
- DOI
- 10.1002/anie.201002739
- Resolver ID
- CaltechAUTHORS:20100830-142224179
- R01 GM073932-04S1
- NIH
- Novartis
- Amgen
- Army Research Office (ARO)
- Office of Naval Research (ONR)
- Created
-
2010-09-15Created from EPrint's datestamp field
- Updated
-
2021-11-08Created from EPrint's last_modified field