Published June 2009
| Accepted Version + Supplemental Material
Journal Article
Open
Electron cryotomography: a new view into microbial ultrastructure
- Creators
- Li, Zhuo
-
Jensen, Grant J.
Abstract
Electron cryotomography (ECT) is an emerging technology that allows thin samples such as small bacterial cells to be imaged in 3D in a nearly native state to 'molecular' (not, vert, similar4 nm) resolution. As such, ECT is beginning to deliver long-awaited insight into the positions and structures of cytoskeletal filaments, cell wall elements, motility machines, chemoreceptor arrays, internal compartments, and other ultrastructures. Here we briefly explain ECT, review its recent contributions to microbiology, and conclude with a discussion of future prospects.
Additional Information
Copyright © 2009 Elsevier. Available online 6 May 2009. We wish to thank Alasdair McDowall, Lu Gan, Morgan Beeby and Ariane Briegel for their help in improving the draft. Ultrastructural research in the Jensen lab is supported by the Howard Hughes Medical Research Institute, NIH grant R01 AI067548 to GJJ, the Beckman Institute at Caltech, and gifts to Caltech from the Gordon and Betty Moore Foundation and Agouron Institute. Supplementary data associated with this article can be found, in the online version, at doi:10.1016/j.mib.2009.03.007.Attached Files
Accepted Version - nihms-128649.pdf
Supplemental Material - Limmc1.mov
Files
nihms-128649.pdf
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Additional details
- PMCID
- PMC2747746
- Eprint ID
- 15616
- Resolver ID
- CaltechAUTHORS:20090904-112844480
- Howard Hughes Medical Institute (HHMI)
- R01 AI067548
- NIH
- Caltech Beckman Institute
- Gordon and Betty Moore Foundation
- Agouron Institute
- Created
-
2009-09-14Created from EPrint's datestamp field
- Updated
-
2021-11-08Created from EPrint's last_modified field