Published June 2009
| Published
Journal Article
Open
Enantioselective γ-lactam synthesis via palladium-catalyzed intramolecular asymmetric allylic alkylation
Abstract
A Pd(0)-catalyzed intramolecular allylic alkylation in the presence of (R)-3,5-t-Bu-MeOBIPHEP takes place in up to 92:8 er in agreement with DFT calculations and provides easy access to enantioenriched disubstituted γ-lactams.
Additional Information
© 2009 Georg Thieme Verlag. Received: 13 February 2009; publication Date: 04 May 2009 (eFirst); 03 June 2009 (Print). CNRS and UPMC are acknowledged for financial support. The sponsorship of COST Action D40 'Innovative Catalysis: New Processes and Selectivities' is kindly acknowledged. PF thanks the Carlsberg and Lundbeck foundations for financial support. We thank Solvias for a gift of ligands, Prof. P. S. Pregosin for a sample of ligand L5, Prof. J.-P. Genêt for a sample of ligand L3, and Prof. P.-O. Norrby for fruitful discussions.Attached Files
Published - Bantreil2009p4729Synlett.pdf
Files
Bantreil2009p4729Synlett.pdf
Files
(153.7 kB)
Name | Size | Download all |
---|---|---|
md5:e7a0a299ac5c48564cd91964e768398a
|
153.7 kB | Preview Download |
Additional details
- Eprint ID
- 14724
- Resolver ID
- CaltechAUTHORS:20090729-121619864
- Centre National de la Recherche Scientifique (CNRS)
- Université Pierre et Marie Curie
- Carlsberg Foundation
- Lundbeck Foundation
- Created
-
2009-08-07Created from EPrint's datestamp field
- Updated
-
2021-11-08Created from EPrint's last_modified field